Great strides have been made in the area of hydrogel science since the first hydrogels were described in the 1960s. Hydrogelation occurs in response to a physical or chemical stimulus, such as temperature, pH, electric or magnetic field, enzymatic modification, light and others. These three-dimensional networks consisting of mainly water molecules represent a unique class of materials, with many applications including cell therapeutics, cartilage/bone regeneration, sustained drug release and drug delivery systems, tissue engineering, 3D bioprinting and extracellular culture medium (ECM) for cancer cells, stem cells and neuronal cells. ChemBioGels 2021 will feature on-going work in the area of hydrogel science.
Great strides have been made in the area of hydrogel science since the first hydrogels were described in the 1960s. Hydrogelation occurs in response to a physical or chemical stimulus, such as temperature, pH, electric or magnetic field, enzymatic modification, light and others. These three-dimensional networks consisting of mainly water molecules represent a unique class of materials, with many applications including cell therapeutics, cartilage/bone regeneration, sustained drug release and drug delivery systems, tissue engineering, 3D bioprinting and extracellular culture medium (ECM) for cancer cells, stem cells and neuronal cells. ChemBioGels 2021 will feature on-going work in the area of hydrogel science.
Great strides have been made in the area of hydrogel science since the first hydrogels were described in the 1960s. Hydrogelation occurs in response to a physical or chemical stimulus, such as temperature, pH, electric or magnetic field, enzymatic modification, light and others. These three-dimensional networks consisting of mainly water molecules represent a unique class of materials, with many applications including cell therapeutics, cartilage/bone regeneration, sustained drug release and drug delivery systems, tissue engineering, 3D bioprinting and extracellular culture medium (ECM) for cancer cells, stem cells and neuronal cells. ChemBioGels 2021 will feature on-going work in the area of hydrogel science.
Professor Ehud Gazit
Professor Ehud Gazit
Dr. José A. Martins
Dehydropeptide-based self-assembled hydrogels
Short Abstract:
Self-assembled peptide-based hydrogels are archetypical nanostructured materials with a plethora of foreseeable applications in nanomedicine. The Peptide Soft Materials Group at the Department of Chemistry of the University of Minho has contributed to this research field with various studies on minimalist dehydropeptide-based self-assembled hydrogels as nanocarriers for drug delivery applications. In this talk I will make an overview of the work developed by the research group on this topic. I will also discuss recent results on the preparation and characterisation of magnetic dehydropeptide-based hydrogels (with incorporated magnetic nanoparticles) as potential theranostic agents, allying MRI imaging to hyperthermia capabilities.
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Short CV:
José Alberto Martins (JAM) graduated in Biochemistry from the University of Coimbra (Portugal) and obtained a PhD in Chemistry (Organic and Bioorganic Chemistry) from the University of Warwick (UK). JAM is, since the year 2000, a Lecturer at the Department of Chemistry of the University of Minho. JAM was a visiting academic at the Department of Chemistry at Bath University (UK) from 2013-14. JAM is a member of the Peptide Soft Materials Group at the Department of Chemistry of the University of Minho. His main research interests focus on metal complexes and self-assembled nanostructures and nanomaterials (micelles, vesicles, peptide hydrogels) containing metal complexes as medical imaging and theranostic agents. JAM has participated in various research projects funded by national agencies. JAM publishes regularly in academic journals (around 50 publications) and is co-inventor of two patents. JAM has (co)supervised various Masters and PhD students and Postdoc researchers.